igoa Fefa'ataua'iga | UniAPI-PBS |
CAS | 1405-20-5 |
Igoa Oloa | Polymyxin B sulfate |
Fa'aaliga | Pa'epa'e pe toetoe a pa'epa'e pauta |
Solubility | Solu vai |
Fa'aaogāga | Vaila'au |
Su'ega | Ole aofaiga ole polymyxin B1, B2, B3 ma le B1-I: 80.0% minPolymyxin B3: 6.0% maxPolymyxin B1-I: 15.0% le maualuga |
afifi | 1kg net ile apa alumini |
Ola fa'asa | 2 tausaga |
Teuina | Teu i se nofoaga malulu ma mago, mamao mai le malamalama. 2~8 ℃ mo le teuina. |
Fa'atonuga vaila'au |
Fa'aaogāga
O le Polyxin B sulfate o se vailaʻau faʻamaʻi faʻamaʻi, o se faʻafefiloi o le polyxin B1 ma le B2, lea e mafai ona faʻaleleia ai le faʻaogaina o le membrane cell. Toetoe lava leai se manogi. Ma'ale'ale i le malamalama. Hygroscopic. Solu i le vai, solu teisi i le ethanol.
A'afiaga ile falema'i
O lona alaleo antibacterial ma le faʻaogaina o falemaʻi e tutusa ma le polymyxin e. o lo'o i ai a'afiaga fa'alavelave po'o fa'ama'i i siama Gram-negative, e pei o le Escherichia coli, Pseudomonas aeruginosa, paraescherichia coli, Klebsiella pneumoniae, acidophilus, pertussis and dysentery. Clinically, e masani ona faʻaaogaina mo faʻamaʻi pipisi e mafua mai i siama maʻaleʻale, faʻamaʻi pipisi o le urinary e mafua mai i le Pseudomonas aeruginosa, mata, trachea, maningitis, sepsis, mu faʻamaʻi, paʻu ma mucous membrane siama, ma isi.
gaioiga fa'afoma'i
O loʻo i ai aʻafiaga antibacterial i Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Haemophilus, enterobacter, Salmonella, Shigella, pertussis, pasteurella ma Vibrio. Proteus, Neisseria, Serratia, pruvidens, Gram-positive bacteria ma obligate anaerobes e leʻi aʻafia i nei vailaʻau. Sa iai le fa'afeagai fa'afeagai i le va o lenei vaila'au ma le polymyxin E, ae leai se fa'afeagai i le va o lenei vaila'au ma isi vaila'au.
E masani ona faʻaaogaina mo manuʻa, urinary tract, mata, taliga, faʻamaʻi pipisi e mafua mai i le Pseudomonas aeruginosa ma isi Pseudomonas. E mafai foi ona faʻaaogaina mo sepsis ma peritonitis.